Oleocanthal is one of the most powerful compounds found in extra virgin olive oil, widely known for its anti-inflammatory and antioxidant effects. Recent scientific studies have revealed an even more remarkable property: its ability to directly target and destroy cancer cells.

What the study by Goren and colleagues showed

Researchers discovered that oleocanthal – as well as extra virgin olive oils naturally rich in it – causes a sudden loss of viability in cancer cells. This happens because oleocanthal affects the lysosomes, the small “recycling centers” inside each cell.

Normally, lysosomes safely store enzymes that break down and recycle cellular waste. When oleocanthal increases the permeability of the lysosomal membrane, these enzymes leak out, leading to cell death.

Why this matters

The striking finding is that oleocanthal appears to selectively target cancer cells while leaving healthy ones unharmed. In experimental mouse models with pancreatic neuroendocrine tumors, treatment with oleocanthal not only reduced tumor size but also extended survival time.

Conclusion

This research supports the view that oleocanthal-rich extra virgin olive oils are far more than a healthy dietary choice – they may act as a natural ally in the fight against cancer. While more clinical trials in humans are needed, the results highlight the immense potential of diet – and especially olive oil – in supporting health and disease prevention.


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