Silent inflammation is a hidden condition: a chronic, low-grade inflammatory state that doesn’t show obvious symptoms but, over time, can cause serious damage to tissues and organs.

Which diseases are linked?
Research shows that silent inflammation is associated with:
•cardiovascular disease
•type 2 diabetes
•obesity
•neurodegenerative disorders (Alzheimer’s, Parkinson’s)
•cancer
•autoimmune diseases

The role of diet
The Mediterranean diet is considered the “antidote” to silent inflammation. At its core lies extra virgin olive oil, especially when it is rich in polyphenols.

Compounds such as oleocanthal and oleacein have proven anti-inflammatory effects similar to non-steroidal anti-inflammatory drugs (NSAIDs), but without their side effects.

-They reduce inflammatory markers (CRP, cytokines).
-They protect the cardiovascular system.
-They help regulate blood sugar and lipid profile.
-They have neuroprotective properties, shielding the brain from inflammation-related damage.

What does science show?
-The PREDIMED trial (NEJM, 2013) demonstrated that a Mediterranean diet supplemented with extra virgin olive oil significantly reduced the risk of cardiovascular events.
-The Greek pilot study MICOIL (2019) showed improved cognitive function in patients with mild cognitive impairment after daily consumption of high-phenolic olive oil.
-Clinical trials in Greece (ELETTRA Kalamata, Athens) have confirmed the positive impact of polyphenolic olive oil on inflammation markers and lipid profile.

Practical steps
•1–2 tablespoons of high-phenolic extra virgin olive oil daily
•Combine with fruits, vegetables, legumes, and fish
•Regular exercise, quality sleep, and stress management


Conclusion
Silent inflammation is an “invisible” risk, but nature provides powerful weapons. High-phenolic olive oil, as a cornerstone of the Mediterranean diet, is not just food – it is a natural medicine, capable of protecting the heart, the brain, and the entire body from the consequences of chronic inflammation.

References
-Hotamisligil GS. Inflammation and metabolic disorders. Nature. 2006.
-Furman D, et al. Chronic inflammation in the etiology of disease across the life span. Nat Med. 2019.
-Estruch R, et al. Primary prevention of cardiovascular disease with a Mediterranean diet. NEJM. 2013.
-Tsolaki M, et al. MICOIL Pilot Study. J Alzheimers Dis. 2019.